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Characterization of Complete Histone Tail Proteoforms Using Differential Ion Mobility Spectrometry

[Image: see text] Histone proteins are subject to dynamic post-translational modifications (PTMs) that cooperatively modulate the chromatin structure and function. Nearly all functional PTMs are found on the N-terminal histone domains (tails) of ∼50 residues protruding from the nucleosome core. Usin...

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Detalles Bibliográficos
Autores principales:	Shliaha, Pavel V., Baird, Matthew A., Nielsen, Mogens M., Gorshkov, Vladimir, Bowman, Andrew P., Kaszycki, Julia L., Jensen, Ole N., Shvartsburg, Alexandre A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436587/ https://www.ncbi.nlm.nih.gov/pubmed/28406606 http://dx.doi.org/10.1021/acs.analchem.7b00379

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