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Haemophilus parasuis cytolethal distending toxin induces cell cycle arrest and p53-dependent apoptosis
Haemophilus parasuis is the causative agent of Glasser’s disease in pigs. Cytolethal distending toxin (CDT) is an important virulence factor of H. parasuis. It is composed of three subunits: CdtA, CdtB and CdtC and all were successfully expressed in soluble form in Escherichia coli when the signal p...
Autores principales: | Li, Gang, Niu, Hui, Zhang, Yanhe, Li, Yanling, Xie, Fang, Langford, Paul R., Liu, Siguo, Wang, Chunlai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436662/ https://www.ncbi.nlm.nih.gov/pubmed/28545143 http://dx.doi.org/10.1371/journal.pone.0177199 |
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