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The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells

Many types of cancer express high levels of heat shock proteins (HSPs) that are molecular chaperones regulating protein folding and stability ensuring protection of cells from potentially lethal stress. HSPs in cancer cells promote survival, growth and spreading even in situations of growth factors...

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Detalles Bibliográficos
Autores principales:	Schaefer, Susanne, Svenstrup, Tina H., Guerra, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436671/ https://www.ncbi.nlm.nih.gov/pubmed/28542269 http://dx.doi.org/10.1371/journal.pone.0177706

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