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Expression of HDAC2 but Not HDAC1 Transcript Is Reduced in Dorsolateral Prefrontal Cortex of Patients with Schizophrenia
[Image: see text] Postmortem brain studies support dysregulated expression of the histone deacetylase enzymes, HDAC1 and HDAC2, as a central feature in diseases including schizophrenia, bipolar disorder, and depression. Our objective was to investigate HDAC expression in a large postmortem sample se...
Autores principales: | Schroeder, Frederick A., Gilbert, Tonya M., Feng, Ningping, Taillon, Brendan D., Volkow, Nora D., Innis, Robert B., Hooker, Jacob M., Lipska, Barbara K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436730/ https://www.ncbi.nlm.nih.gov/pubmed/27959513 http://dx.doi.org/10.1021/acschemneuro.6b00372 |
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