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The toxic effects and possible mechanisms of Brusatol on mouse oocytes

Brusatol is a natural quassinoid that shows a potential therapeutic use in cancer models by the inhibition of Nuclear factor erythroid 2-related factor 2 (Nrf2) and is capable of inducing a variety of biological effects. The effects of Brusatol on oocyte meiosis has not been addressed. In this study...

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Detalles Bibliográficos
Autores principales: Ma, Rujun, Li, Hongru, Zhang, Yu, Lin, Ying, Qiu, Xuhua, Xie, Min, Yao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436816/
https://www.ncbi.nlm.nih.gov/pubmed/28542354
http://dx.doi.org/10.1371/journal.pone.0177844