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The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions

The focal adhesion protein testin is a modular scaffold and tumour suppressor that consists of an N-terminal cysteine rich (CR) domain, a PET domain of unknown function and three C-terminal LIM domains. Testin has been proposed to have an open and a closed conformation based on the observation that...

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Detalles Bibliográficos
Autores principales: Sala, Stefano, Catillon, Marie, Hadzic, Ermin, Schaffner-Reckinger, Elisabeth, Van Troys, Marleen, Ampe, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436826/
https://www.ncbi.nlm.nih.gov/pubmed/28542564
http://dx.doi.org/10.1371/journal.pone.0177879