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The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions
The focal adhesion protein testin is a modular scaffold and tumour suppressor that consists of an N-terminal cysteine rich (CR) domain, a PET domain of unknown function and three C-terminal LIM domains. Testin has been proposed to have an open and a closed conformation based on the observation that...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436826/ https://www.ncbi.nlm.nih.gov/pubmed/28542564 http://dx.doi.org/10.1371/journal.pone.0177879 |