Cargando…

The PET and LIM1-2 domains of testin contribute to intramolecular and homodimeric interactions

The focal adhesion protein testin is a modular scaffold and tumour suppressor that consists of an N-terminal cysteine rich (CR) domain, a PET domain of unknown function and three C-terminal LIM domains. Testin has been proposed to have an open and a closed conformation based on the observation that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sala, Stefano, Catillon, Marie, Hadzic, Ermin, Schaffner-Reckinger, Elisabeth, Van Troys, Marleen, Ampe, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436826/ https://www.ncbi.nlm.nih.gov/pubmed/28542564 http://dx.doi.org/10.1371/journal.pone.0177879

Ejemplares similares

Delineating the Tes Interaction Site in Zyxin and Studying Cellular Effects of Its Disruption
por: Hadzic, Ermin, et al.
Publicado: (2015)

Stress fiber strain recognition by the LIM protein testin is cryptic and mediated by RhoA
por: Sala, Stefano, et al.
Publicado: (2021)

Quantitative Kinetic Study of the Actin-Bundling Protein L-Plastin and of Its Impact on Actin Turn-Over
por: Al Tanoury, Ziad, et al.
Publicado: (2010)

Testin on Atherosclerosis in Rabbits
por: Zhang, Yue, et al.
Publicado: (2015)

The Role of Testin in Human Cancers
por: Popiel, Aneta, et al.
Publicado: (2018)

Prevalence of Cytoplasmic Actin Mutations in Diffuse Large B-Cell Lymphoma and Multiple Myeloma: A Functional Assessment Based on Actin Three-Dimensional Structures
por: Witjes, Laura, et al.
Publicado: (2020)

Rat and mouse testicular testin is different from the human tumor suppressor gene TESTIN (Tes): Authors’ response to the letter of Dr. S. Kapoor
por: Mruk, Dolores D., et al.
Publicado: (2012)

CellMissy: a tool for management, storage and analysis of cell migration data produced in wound healing-like assays
por: Masuzzo, Paola, et al.
Publicado: (2013)

An end-to-end software solution for the analysis of high-throughput single-cell migration data
por: Masuzzo, Paola, et al.
Publicado: (2017)

Combination of EGFR Inhibitor Lapatinib and MET Inhibitor Foretinib Inhibits Migration of Triple Negative Breast Cancer Cell Lines
por: Simiczyjew, Aleksandra, et al.
Publicado: (2018)

Testin and its emerging modulatory role in systemic carcinogenesis
por: Kapoor, Shailendra
Publicado: (2012)

Archaeal RNA ligase is a homodimeric protein that catalyzes intramolecular ligation of single-stranded RNA and DNA
por: Torchia, Christopher, et al.
Publicado: (2008)

Structure and functional relevance of the Slit2 homodimerization domain
por: Seiradake, Elena, et al.
Publicado: (2009)

Structure of the homodimeric androgen receptor ligand-binding domain
por: Nadal, Marta, et al.
Publicado: (2017)

β-Agonists Selectively Modulate Proinflammatory Gene Expression in Skeletal Muscle Cells via Non-Canonical Nuclear Crosstalk Mechanisms
por: Kolmus, Krzysztof, et al.
Publicado: (2014)

Correction: β-Agonists Selectively Modulate Proinflammatory Gene Expression in Skeletal Muscle Cells via Non-Canonical Nuclear Crosstalk Mechanisms
por: Kolmus, Krzysztof, et al.
Publicado: (2023)

The Expression of Testin, Ki-67 and p16 in Cervical Cancer Diagnostics
por: Popiel-Kopaczyk, Aneta, et al.
Publicado: (2023)

Analysis of the Drosophila Ajuba LIM protein defines functions for distinct LIM domains
por: Rauskolb, Cordelia, et al.
Publicado: (2022)

Testin (TES) as a candidate tumour suppressor and prognostic marker in human astrocytoma
por: Steponaitis, Giedrius, et al.
Publicado: (2016)

Four Cysteine Residues Contribute to Homodimerization of Chicken Interleukin-2
por: Deng, Chen, et al.
Publicado: (2019)

Structural basis for chemically-induced homodimerization of a single domain antibody
por: Lesne, Jean, et al.
Publicado: (2019)

The Cytoplasmic LIM Domain Protein Espinas Contributes to Photoreceptor Layer Selection in the Visual System
por: Fernández-Pineda, Alejandra, et al.
Publicado: (2020)

Testin protects against cardiac hypertrophy by targeting a calcineurin‐dependent signalling pathway
por: Gao, Lu, et al.
Publicado: (2018)

Preliminary Study on the Expression of Testin, p16 and Ki-67 in the Cervical Intraepithelial Neoplasia
por: Popiel, Aneta, et al.
Publicado: (2021)

Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila
por: Bonchuk, Artem, et al.
Publicado: (2021)

Study of the N-Terminal Domain Homodimerization in Human Proteins with Zinc Finger Clusters
por: Fursenko, D. V., et al.
Publicado: (2021)

Contribution of the LIM Domain and Nebulin-Repeats to the Interaction of Lasp-2 with Actin Filaments and Focal Adhesions
por: Nakagawa, Hiroyuki, et al.
Publicado: (2009)

LIM domain only 1: an oncogenic transcription cofactor contributing to the tumorigenesis of multiple cancer types
por: Zhao, Guo-Fa, et al.
Publicado: (2021)

TESTIN suppresses tumor growth and invasion via manipulating cell cycle progression in endometrial carcinoma
por: Gu, Zhenpeng, et al.
Publicado: (2014)

TESTIN Induces Rapid Death and Suppresses Proliferation in Childhood B Acute Lymphoblastic Leukaemia Cells
por: Weeks, Robert J., et al.
Publicado: (2016)

The focal adhesion protein Testin modulates KCNE2 potassium channel β subunit activity
por: Papanikolaou, Maria, et al.
Publicado: (2021)

Innovative mouse models for the tumor suppressor activity of Protocadherin-10 isoforms
por: Kleinberger, Irene, et al.
Publicado: (2022)

SH3-domain mutations selectively disrupt Csk homodimerization or PTPN22 binding
por: Brian, Ben F., et al.
Publicado: (2022)

The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression
por: Holik, Aliaksei Z., et al.
Publicado: (2015)

Four and a Half LIM Domains 2 (FHL2) Contribute to the Epithelial Ovarian Cancer Carcinogenesis
por: Wang, Chen, et al.
Publicado: (2020)

Silencing of Testin expression is a frequent event in spontaneous lymphomas from Trp53-mutant mice
por: Weeks, Robert J., et al.
Publicado: (2020)

LIM1 contributes to the malignant potential of endometrial cancer
por: Kato, Hiroaki, et al.
Publicado: (2023)

Actin Cytoskeletal Reorganization Function of JRAB/MICAL-L2 Is Fine-tuned by Intramolecular Interaction between First LIM Zinc Finger and C-terminal Coiled-coil Domains
por: Miyake, Kazuhisa, et al.
Publicado: (2019)

A requirement for Lim domain binding protein 1 in erythropoiesis
por: Li, LiQi, et al.
Publicado: (2010)

LIM Homeobox Domain 2 Is Required for Corneal Epithelial Homeostasis
por: Sartaj, Rachel, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_23v6g7vg7tlirqfca3oe52hi70