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The feasibility of endoscopy-CT image registration in the head and neck without prospective endoscope tracking

PURPOSE: Endoscopic examinations are frequently-used procedures for patients with head and neck cancer undergoing radiotherapy, but radiation treatment plans are created on computed tomography (CT) scans. Image registration between endoscopic video and CT could be used to improve treatment planning...

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Autores principales: Ingram, W. Scott, Yang, Jinzhong, Beadle, Beth M., Wendt, Richard, Rao, Arvind, Wang, Xin A., Court, Laurence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436843/
https://www.ncbi.nlm.nih.gov/pubmed/28542331
http://dx.doi.org/10.1371/journal.pone.0177886
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author Ingram, W. Scott
Yang, Jinzhong
Beadle, Beth M.
Wendt, Richard
Rao, Arvind
Wang, Xin A.
Court, Laurence E.
author_facet Ingram, W. Scott
Yang, Jinzhong
Beadle, Beth M.
Wendt, Richard
Rao, Arvind
Wang, Xin A.
Court, Laurence E.
author_sort Ingram, W. Scott
collection PubMed
description PURPOSE: Endoscopic examinations are frequently-used procedures for patients with head and neck cancer undergoing radiotherapy, but radiation treatment plans are created on computed tomography (CT) scans. Image registration between endoscopic video and CT could be used to improve treatment planning and analysis of radiation-related normal tissue toxicity. The purpose of this study was to explore the feasibility of endoscopy-CT image registration without prospective physical tracking of the endoscope during the examination. METHODS: A novel registration technique called Location Search was developed. This technique uses physical constraints on the endoscope’s view direction to search for the virtual endoscope coordinates that maximize the similarity between the endoscopic video frame and the virtual endoscopic image. Its performance was tested on phantom and patient images and compared to an established registration technique, Frame-To-Frame Tracking. RESULTS: In phantoms, Location Search had average registration errors of 0.55 ± 0.60 cm for point measurements and 0.29 ± 0.15 cm for object surface measurements. Frame-To-Frame Tracking achieved similar results on some frames, but it failed on others due to the virtual endoscope becoming lost. This weakness was more pronounced in patients, where Frame-To-Frame tracking could not make it through the nasal cavity. On successful patient video frames, Location Search was able to find endoscope positions with an average distance of 0.98 ± 0.53 cm away from the ground truth positions. However, it failed on many frames due to false similarity matches caused by anatomical structural differences between the endoscopic video and the virtual endoscopic images. CONCLUSIONS: Endoscopy-CT image registration without prospective physical tracking of the endoscope is possible, but more development is required to achieve an accuracy suitable for clinical translation.
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spelling pubmed-54368432017-05-27 The feasibility of endoscopy-CT image registration in the head and neck without prospective endoscope tracking Ingram, W. Scott Yang, Jinzhong Beadle, Beth M. Wendt, Richard Rao, Arvind Wang, Xin A. Court, Laurence E. PLoS One Research Article PURPOSE: Endoscopic examinations are frequently-used procedures for patients with head and neck cancer undergoing radiotherapy, but radiation treatment plans are created on computed tomography (CT) scans. Image registration between endoscopic video and CT could be used to improve treatment planning and analysis of radiation-related normal tissue toxicity. The purpose of this study was to explore the feasibility of endoscopy-CT image registration without prospective physical tracking of the endoscope during the examination. METHODS: A novel registration technique called Location Search was developed. This technique uses physical constraints on the endoscope’s view direction to search for the virtual endoscope coordinates that maximize the similarity between the endoscopic video frame and the virtual endoscopic image. Its performance was tested on phantom and patient images and compared to an established registration technique, Frame-To-Frame Tracking. RESULTS: In phantoms, Location Search had average registration errors of 0.55 ± 0.60 cm for point measurements and 0.29 ± 0.15 cm for object surface measurements. Frame-To-Frame Tracking achieved similar results on some frames, but it failed on others due to the virtual endoscope becoming lost. This weakness was more pronounced in patients, where Frame-To-Frame tracking could not make it through the nasal cavity. On successful patient video frames, Location Search was able to find endoscope positions with an average distance of 0.98 ± 0.53 cm away from the ground truth positions. However, it failed on many frames due to false similarity matches caused by anatomical structural differences between the endoscopic video and the virtual endoscopic images. CONCLUSIONS: Endoscopy-CT image registration without prospective physical tracking of the endoscope is possible, but more development is required to achieve an accuracy suitable for clinical translation. Public Library of Science 2017-05-18 /pmc/articles/PMC5436843/ /pubmed/28542331 http://dx.doi.org/10.1371/journal.pone.0177886 Text en © 2017 Ingram et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Ingram, W. Scott
Yang, Jinzhong
Beadle, Beth M.
Wendt, Richard
Rao, Arvind
Wang, Xin A.
Court, Laurence E.
The feasibility of endoscopy-CT image registration in the head and neck without prospective endoscope tracking
title The feasibility of endoscopy-CT image registration in the head and neck without prospective endoscope tracking
title_full The feasibility of endoscopy-CT image registration in the head and neck without prospective endoscope tracking
title_fullStr The feasibility of endoscopy-CT image registration in the head and neck without prospective endoscope tracking
title_full_unstemmed The feasibility of endoscopy-CT image registration in the head and neck without prospective endoscope tracking
title_short The feasibility of endoscopy-CT image registration in the head and neck without prospective endoscope tracking
title_sort feasibility of endoscopy-ct image registration in the head and neck without prospective endoscope tracking
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436843/
https://www.ncbi.nlm.nih.gov/pubmed/28542331
http://dx.doi.org/10.1371/journal.pone.0177886
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