A mathematical model coupling polarity signaling to cell adhesion explains diverse cell migration patterns

Protrusion and retraction of lamellipodia are common features of eukaryotic cell motility. As a cell migrates through its extracellular matrix (ECM), lamellipod growth increases cell-ECM contact area and enhances engagement of integrin receptors, locally amplifying ECM input to internal signaling ca...

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Detalles Bibliográficos
Autores principales: Holmes, William R., Park, JinSeok, Levchenko, Andre, Edelstein-Keshet, Leah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436877/
https://www.ncbi.nlm.nih.gov/pubmed/28472054
http://dx.doi.org/10.1371/journal.pcbi.1005524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436877/
https://www.ncbi.nlm.nih.gov/pubmed/28472054
http://dx.doi.org/10.1371/journal.pcbi.1005524

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