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MUG-Mel2, a novel highly pigmented and well characterized NRAS mutated human melanoma cell line

NRAS mutation in melanoma has been associated with aggressive tumor biology and poor prognosis. Although targeted therapy has been tested for NRAS mutated melanoma, response rates still appear much weaker, than in BRAF mutated melanoma. While plenty of cell lines exist, however, only few melanogenic...

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Detalles Bibliográficos
Autores principales: Rinner, Beate, Gandolfi, Greta, Meditz, Katharina, Frisch, Marie-Therese, Wagner, Karin, Ciarrocchi, Alessia, Torricelli, Federica, Koivuniemi, Raili, Niklander, Johanna, Liegl-Atzwanger, Bernadette, Lohberger, Birgit, Heitzer, Ellen, Ghaffari-Tabrizi-Wizsy, Nassim, Zweytick, Dagmar, Zalaudek, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437015/
https://www.ncbi.nlm.nih.gov/pubmed/28522871
http://dx.doi.org/10.1038/s41598-017-02197-y