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Parkin regulation of CHOP modulates susceptibility to cardiac endoplasmic reticulum stress
The regulatory control of cardiac endoplasmic reticulum (ER) stress is incompletely characterized. As ER stress signaling upregulates the E3-ubiquitin ligase Parkin, we investigated the role of Parkin in cardiac ER stress. Parkin knockout mice exposed to aortic constriction-induced cardiac pressure-...
Autores principales: | Han, Kim, Hassanzadeh, Shahin, Singh, Komudi, Menazza, Sara, Nguyen, Tiffany T., Stevens, Mark V., Nguyen, An, San, Hong, Anderson, Stasia A., Lin, Yongshun, Zou, Jizhong, Murphy, Elizabeth, Sack, Michael N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437023/ https://www.ncbi.nlm.nih.gov/pubmed/28522833 http://dx.doi.org/10.1038/s41598-017-02339-2 |
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