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Kv3.4 is modulated by HIF-1α to protect SH-SY5Y cells against oxidative stress-induced neural cell death

The Kv3.4 channel is characterized by fast inactivation and sensitivity to oxidation. However, the physiological role of Kv3.4 as an oxidation-sensitive channel has yet to be investigated. Here, we demonstrate that Kv3.4 plays a pivotal role in oxidative stress-related neural cell damage as an oxida...

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Detalles Bibliográficos
Autores principales: Song, Min Seok, Ryu, Pan Dong, Lee, So Yeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437029/
https://www.ncbi.nlm.nih.gov/pubmed/28522852
http://dx.doi.org/10.1038/s41598-017-02129-w

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