Disruption of melatonin synthesis is associated with impaired 14-3-3 and miR-451 levels in patients with autism spectrum disorders

Autism spectrum disorders (ASD) are characterized by a wide genetic and clinical heterogeneity. However, some biochemical impairments, including decreased melatonin (crucial for circadian regulation) and elevated platelet N-acetylserotonin (the precursor of melatonin) have been reported as very freq...

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Detalles Bibliográficos
Autores principales: Pagan, Cécile, Goubran-Botros, Hany, Delorme, Richard, Benabou, Marion, Lemière, Nathalie, Murray, Kerren, Amsellem, Frédérique, Callebert, Jacques, Chaste, Pauline, Jamain, Stéphane, Fauchereau, Fabien, Huguet, Guillaume, Maronde, Erik, Leboyer, Marion, Launay, Jean-Marie, Bourgeron, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437096/
https://www.ncbi.nlm.nih.gov/pubmed/28522826
http://dx.doi.org/10.1038/s41598-017-02152-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437096/
https://www.ncbi.nlm.nih.gov/pubmed/28522826
http://dx.doi.org/10.1038/s41598-017-02152-x

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