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Voluntary Exercise Promotes Glymphatic Clearance of Amyloid Beta and Reduces the Activation of Astrocytes and Microglia in Aged Mice
Age is characterized by chronic inflammation, leading to synaptic dysfunction and dementia because the clearance of protein waste is reduced. The clearance of proteins depends partly on the permeation of the blood–brain barrier (BBB) or on the exchange of water and soluble contents between the cereb...
Autores principales: | He, Xiao-fei, Liu, Dong-xu, Zhang, Qun, Liang, Feng-ying, Dai, Guang-yan, Zeng, Jin-sheng, Pei, Zhong, Xu, Guang-qing, Lan, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437122/ https://www.ncbi.nlm.nih.gov/pubmed/28579942 http://dx.doi.org/10.3389/fnmol.2017.00144 |
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