Mimicking Cardiac Fibrosis in a Dish: Fibroblast Density Rather than Collagen Density Weakens Cardiomyocyte Function

Cardiac fibrosis is one of the most devastating effects of cardiac disease. Current in vitro models of cardiac fibrosis do not sufficiently mimic the complex in vivo environment of the cardiomyocyte. We determined the local composition and mechanical properties of the myocardium in established mouse...

Descripción completa

Detalles Bibliográficos
Autores principales: van Spreeuwel, Ariane C.C., Bax, Noortje A.M., van Nierop, Bastiaan J., Aartsma-Rus, Annemieke, Goumans, Marie-José T.H., Bouten, Carlijn V.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437129/
https://www.ncbi.nlm.nih.gov/pubmed/28281243
http://dx.doi.org/10.1007/s12265-017-9737-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437129/
https://www.ncbi.nlm.nih.gov/pubmed/28281243
http://dx.doi.org/10.1007/s12265-017-9737-1

Ejemplares similares