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Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation

Myeloperoxidase (MPO) is synthesized by neutrophil and monocyte precursor cells and contributes to host defense by mediating microbial killing. Although several steps in MPO biosynthesis and processing have been elucidated, many questions remained, such as the structure-function relationship of mono...

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Detalles Bibliográficos
Autores principales:	Grishkovskaya, Irina, Paumann-Page, Martina, Tscheliessnig, Rupert, Stampler, Johanna, Hofbauer, Stefan, Soudi, Monika, Sevcnikar, Benjamin, Oostenbrink, Chris, Furtmüller, Paul G., Djinović-Carugo, Kristina, Nauseef, William M., Obinger, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437232/ https://www.ncbi.nlm.nih.gov/pubmed/28348079 http://dx.doi.org/10.1074/jbc.M117.775031

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