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C. elegans chromosomes connect to centrosomes by anchoring into the spindle network
The mitotic spindle ensures the faithful segregation of chromosomes. Here we combine the first large-scale serial electron tomography of whole mitotic spindles in early C. elegans embryos with live-cell imaging to reconstruct all microtubules in 3D and identify their plus- and minus-ends. We classif...
Autores principales: | Redemann, Stefanie, Baumgart, Johannes, Lindow, Norbert, Shelley, Michael, Nazockdast, Ehssan, Kratz, Andrea, Prohaska, Steffen, Brugués, Jan, Fürthauer, Sebastian, Müller-Reichert, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437269/ https://www.ncbi.nlm.nih.gov/pubmed/28492281 http://dx.doi.org/10.1038/ncomms15288 |
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