Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania

The indigenous populations of the South Pacific experience a high burden of rheumatic heart disease (RHD). Here we report a genome-wide association study (GWAS) of RHD susceptibility in 2,852 individuals recruited in eight Oceanian countries. Stratifying by ancestry, we analysed genotyped and impute...

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Detalles Bibliográficos
Autores principales: Parks, Tom, Mirabel, Mariana M., Kado, Joseph, Auckland, Kathryn, Nowak, Jaroslaw, Rautanen, Anna, Mentzer, Alexander J., Marijon, Eloi, Jouven, Xavier, Perman, Mai Ling, Cua, Tuliana, Kauwe, John K., Allen, John B., Taylor, Henry, Robson, Kathryn J., Deane, Charlotte M., Steer, Andrew C., Hill, Adrian V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437274/
https://www.ncbi.nlm.nih.gov/pubmed/28492228
http://dx.doi.org/10.1038/ncomms14946

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