BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks

Precisely measuring the location and frequency of DNA double-strand breaks (DSBs) along the genome is instrumental to understanding genomic fragility, but current methods are limited in versatility, sensitivity or practicality. Here we present Breaks Labeling In Situ and Sequencing (BLISS), featurin...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Winston X., Mirzazadeh, Reza, Garnerone, Silvano, Scott, David, Schneider, Martin W., Kallas, Tomasz, Custodio, Joaquin, Wernersson, Erik, Li, Yinqing, Gao, Linyi, Federova, Yana, Zetsche, Bernd, Zhang, Feng, Bienko, Magda, Crosetto, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437291/
https://www.ncbi.nlm.nih.gov/pubmed/28497783
http://dx.doi.org/10.1038/ncomms15058

Ejemplares similares

Ejemplares similares