Cargando…
Highly specific imaging of mRNA in single cells by target RNA-initiated rolling circle amplification
Detection of single-cell gene expression with high spatial and sequence resolution is a key challenge in single cell biology. Herein, we propose a robust method for the direct detection of mRNA, termed target RNA-initiated rolling circle amplification, which enables imaging of mRNA with single-nucle...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437493/ https://www.ncbi.nlm.nih.gov/pubmed/28580104 http://dx.doi.org/10.1039/c7sc00292k |