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Thalassemias in South Asia: clinical lessons learnt from Bangladesh

Thalassemias are emerging as a global public health concern. Due to remarkable success in the reduction of childhood mortality by controlling infectious diseases in developing countries, thalassemias are likely to be a major public health concern in the coming decades in South Asia. Despite the fact...

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Autores principales: Hossain, Mohammad Sorowar, Raheem, Enayetur, Sultana, Tanvira Afroze, Ferdous, Shameema, Nahar, Nusrat, Islam, Sazia, Arifuzzaman, Mohammad, Razzaque, Mohammad Abdur, Alam, Rabiul, Aziz, Sonia, Khatun, Hazera, Rahim, Abdur, Morshed, Manzur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437604/
https://www.ncbi.nlm.nih.gov/pubmed/28521805
http://dx.doi.org/10.1186/s13023-017-0643-z
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author Hossain, Mohammad Sorowar
Raheem, Enayetur
Sultana, Tanvira Afroze
Ferdous, Shameema
Nahar, Nusrat
Islam, Sazia
Arifuzzaman, Mohammad
Razzaque, Mohammad Abdur
Alam, Rabiul
Aziz, Sonia
Khatun, Hazera
Rahim, Abdur
Morshed, Manzur
author_facet Hossain, Mohammad Sorowar
Raheem, Enayetur
Sultana, Tanvira Afroze
Ferdous, Shameema
Nahar, Nusrat
Islam, Sazia
Arifuzzaman, Mohammad
Razzaque, Mohammad Abdur
Alam, Rabiul
Aziz, Sonia
Khatun, Hazera
Rahim, Abdur
Morshed, Manzur
author_sort Hossain, Mohammad Sorowar
collection PubMed
description Thalassemias are emerging as a global public health concern. Due to remarkable success in the reduction of childhood mortality by controlling infectious diseases in developing countries, thalassemias are likely to be a major public health concern in the coming decades in South Asia. Despite the fact that Bangladesh lies in the world’s thalassemia belt, the information on different aspects (epidemiology, clinical course, mortality, complications and treatment outcomes) of thalassemias is lacking. In this comprehensive review, the aim is to to depict the epidemiological aspects of thalassemias, mutation profile and current treatment and management practices in the country by sharing the experience of dealing with 1178 cases over 2009–2014 time periods in a specialized thalassemia treatment centre. We have also discussed the preventative strategies of thalassemias from the context of Bangladesh which could be effective for other developing countries.
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spelling pubmed-54376042017-05-22 Thalassemias in South Asia: clinical lessons learnt from Bangladesh Hossain, Mohammad Sorowar Raheem, Enayetur Sultana, Tanvira Afroze Ferdous, Shameema Nahar, Nusrat Islam, Sazia Arifuzzaman, Mohammad Razzaque, Mohammad Abdur Alam, Rabiul Aziz, Sonia Khatun, Hazera Rahim, Abdur Morshed, Manzur Orphanet J Rare Dis Review Thalassemias are emerging as a global public health concern. Due to remarkable success in the reduction of childhood mortality by controlling infectious diseases in developing countries, thalassemias are likely to be a major public health concern in the coming decades in South Asia. Despite the fact that Bangladesh lies in the world’s thalassemia belt, the information on different aspects (epidemiology, clinical course, mortality, complications and treatment outcomes) of thalassemias is lacking. In this comprehensive review, the aim is to to depict the epidemiological aspects of thalassemias, mutation profile and current treatment and management practices in the country by sharing the experience of dealing with 1178 cases over 2009–2014 time periods in a specialized thalassemia treatment centre. We have also discussed the preventative strategies of thalassemias from the context of Bangladesh which could be effective for other developing countries. BioMed Central 2017-05-18 /pmc/articles/PMC5437604/ /pubmed/28521805 http://dx.doi.org/10.1186/s13023-017-0643-z Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Hossain, Mohammad Sorowar
Raheem, Enayetur
Sultana, Tanvira Afroze
Ferdous, Shameema
Nahar, Nusrat
Islam, Sazia
Arifuzzaman, Mohammad
Razzaque, Mohammad Abdur
Alam, Rabiul
Aziz, Sonia
Khatun, Hazera
Rahim, Abdur
Morshed, Manzur
Thalassemias in South Asia: clinical lessons learnt from Bangladesh
title Thalassemias in South Asia: clinical lessons learnt from Bangladesh
title_full Thalassemias in South Asia: clinical lessons learnt from Bangladesh
title_fullStr Thalassemias in South Asia: clinical lessons learnt from Bangladesh
title_full_unstemmed Thalassemias in South Asia: clinical lessons learnt from Bangladesh
title_short Thalassemias in South Asia: clinical lessons learnt from Bangladesh
title_sort thalassemias in south asia: clinical lessons learnt from bangladesh
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437604/
https://www.ncbi.nlm.nih.gov/pubmed/28521805
http://dx.doi.org/10.1186/s13023-017-0643-z
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