Control of gene expression through the nonsense-mediated RNA decay pathway

Nonsense-mediated RNA decay (NMD) was originally discovered as a cellular surveillance pathway that safeguards the quality of mRNA transcripts in eukaryotic cells. In its canonical function, NMD prevents translation of mutant mRNAs harboring premature termination codons (PTCs) by targeting them for...

Descripción completa

Detalles Bibliográficos
Autores principales: Nickless, Andrew, Bailis, Julie M., You, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437625/
https://www.ncbi.nlm.nih.gov/pubmed/28533900
http://dx.doi.org/10.1186/s13578-017-0153-7

Ejemplares similares

Ejemplares similares