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XLF-mediated NHEJ activity in hepatocellular carcinoma therapy resistance

BACKGROUND: DNA repair pathways are used by cancer cells to overcome many standard anticancer treatments, causing therapy resistance. Here, we investigated the role of XRCC4-like factor (XLF), a core member of the non-homologous end joining (NHEJ) repair pathway, in chemoresistance in hepatocellular...

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Detalles Bibliográficos
Autores principales:	Yang, Sitian, Wang, Xiao Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437682/ https://www.ncbi.nlm.nih.gov/pubmed/28526069 http://dx.doi.org/10.1186/s12885-017-3345-y

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