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Epigenetic regulation of the circadian clock: role of 5-aza-2′-deoxycytidine

We have been investigating transcriptional regulation of the BMAL1 gene, a critical component of the mammalian clock system including DNA methylation. Here, a more detailed analysis of the regulation of DNA methylation of BMAL1 proceeded in RPMI8402 lymphoma cells. We found that CpG islands in the B...

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Detalles Bibliográficos
Autores principales: Tomita, Tatsunosuke, Kurita, Ryoji, Onishi, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437938/
https://www.ncbi.nlm.nih.gov/pubmed/28487473
http://dx.doi.org/10.1042/BSR20170053