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Fine-tuning of gene expression dynamics by the Set2-Rpd3S pathway
RNA polymerase II-interacting the Set2 methyltransferase co-transcriptionally methylates histone H3 at lysine 36 within the body of genes. This modification facilitates histone deacetylation by Rpd3S HDAC in 3′ transcribed regions to suppress cryptic initiation and slow elongation. Although this pat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437959/ https://www.ncbi.nlm.nih.gov/pubmed/28320505 http://dx.doi.org/10.5483/BMBRep.2017.50.4.049 |