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Fine-tuning of gene expression dynamics by the Set2-Rpd3S pathway

RNA polymerase II-interacting the Set2 methyltransferase co-transcriptionally methylates histone H3 at lysine 36 within the body of genes. This modification facilitates histone deacetylation by Rpd3S HDAC in 3′ transcribed regions to suppress cryptic initiation and slow elongation. Although this pat...

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Detalles Bibliográficos
Autores principales:	Lee, Bo Bae, Kim, Ji Hyun, Kim, TaeSoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2017
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437959/ https://www.ncbi.nlm.nih.gov/pubmed/28320505 http://dx.doi.org/10.5483/BMBRep.2017.50.4.049

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