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Nonsense-mediated mRNA decay at the crossroads of many cellular pathways
Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism ensuring the fast decay of mRNAs harboring a premature termination codon (PTC). As a quality control mechanism, NMD distinguishes PTCs from normal termination codons in order to degrade PTC-carrying mRNAs only. For this, NMD is connected...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korean Society for Biochemistry and Molecular Biology
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437961/ https://www.ncbi.nlm.nih.gov/pubmed/28115040 http://dx.doi.org/10.5483/BMBRep.2017.50.4.015 |