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Analyses of alternative polyadenylation: from old school biochemistry to high-throughput technologies

Alternations in usage of polyadenylation sites during transcription termination yield transcript isoforms from a gene. Recent findings of transcriptome-wide alternative polyadenylation (APA) as a molecular response to changes in biology position APA not only as a molecular event of early transcripti...

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Detalles Bibliográficos
Autores principales: Yeh, Hsin-Sung, Zhang, Wei, Yong, Jeongsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437964/
https://www.ncbi.nlm.nih.gov/pubmed/28148393
http://dx.doi.org/10.5483/BMBRep.2017.50.4.019