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Management of streptococcal pneumoniae-induced hemolytic uremic syndrome: a case report

Hemolytic uremic syndrome (HUS) secondary to Streptococcus pneumoniae infections (pHUS) has been well reported in the literature and accounts for roughly 5% of all the cases of HUS. However, this condition is likely under-diagnosed and the incidence is believed to be increasing. Given this increase...

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Autores principales: Weintraub, Lauren, Ahluwalia, Manpreet, Dogra, Samriti, Uehlinger, Joan, Skversky, Amy, Vasovic, Ljiljana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437990/
https://www.ncbi.nlm.nih.gov/pubmed/29043123
http://dx.doi.org/10.5414/CNCS107887
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author Weintraub, Lauren
Ahluwalia, Manpreet
Dogra, Samriti
Uehlinger, Joan
Skversky, Amy
Vasovic, Ljiljana
author_facet Weintraub, Lauren
Ahluwalia, Manpreet
Dogra, Samriti
Uehlinger, Joan
Skversky, Amy
Vasovic, Ljiljana
author_sort Weintraub, Lauren
collection PubMed
description Hemolytic uremic syndrome (HUS) secondary to Streptococcus pneumoniae infections (pHUS) has been well reported in the literature and accounts for roughly 5% of all the cases of HUS. However, this condition is likely under-diagnosed and the incidence is believed to be increasing. Given this increase in incidence of pHUS, it is important to have an understanding of the optimal means to manage the disease. We report a case of a 2-year-old male with pneumonia, acute kidney injury (AKI), microangiopathic hemolytic anemia (MAHA), and thrombocytopenia, diagnosed with pHUS and successfully treated with antibiotics, washed red blood cell (RBC) transfusions, plasma exchange (PE) with 5% albumin replacement, steroids, and hemodialysis. The response seen in our patient adds to the current literature and further supports the use of PE with albumin in patients with pHUS.
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spelling pubmed-54379902017-10-17 Management of streptococcal pneumoniae-induced hemolytic uremic syndrome: a case report Weintraub, Lauren Ahluwalia, Manpreet Dogra, Samriti Uehlinger, Joan Skversky, Amy Vasovic, Ljiljana Clin Nephrol Case Stud Case Report Hemolytic uremic syndrome (HUS) secondary to Streptococcus pneumoniae infections (pHUS) has been well reported in the literature and accounts for roughly 5% of all the cases of HUS. However, this condition is likely under-diagnosed and the incidence is believed to be increasing. Given this increase in incidence of pHUS, it is important to have an understanding of the optimal means to manage the disease. We report a case of a 2-year-old male with pneumonia, acute kidney injury (AKI), microangiopathic hemolytic anemia (MAHA), and thrombocytopenia, diagnosed with pHUS and successfully treated with antibiotics, washed red blood cell (RBC) transfusions, plasma exchange (PE) with 5% albumin replacement, steroids, and hemodialysis. The response seen in our patient adds to the current literature and further supports the use of PE with albumin in patients with pHUS. Dustri-Verlag Dr. Karl Feistle 2014-04-14 /pmc/articles/PMC5437990/ /pubmed/29043123 http://dx.doi.org/10.5414/CNCS107887 Text en © Dustri-Verlag Dr. K. Feistle http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Weintraub, Lauren
Ahluwalia, Manpreet
Dogra, Samriti
Uehlinger, Joan
Skversky, Amy
Vasovic, Ljiljana
Management of streptococcal pneumoniae-induced hemolytic uremic syndrome: a case report
title Management of streptococcal pneumoniae-induced hemolytic uremic syndrome: a case report
title_full Management of streptococcal pneumoniae-induced hemolytic uremic syndrome: a case report
title_fullStr Management of streptococcal pneumoniae-induced hemolytic uremic syndrome: a case report
title_full_unstemmed Management of streptococcal pneumoniae-induced hemolytic uremic syndrome: a case report
title_short Management of streptococcal pneumoniae-induced hemolytic uremic syndrome: a case report
title_sort management of streptococcal pneumoniae-induced hemolytic uremic syndrome: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437990/
https://www.ncbi.nlm.nih.gov/pubmed/29043123
http://dx.doi.org/10.5414/CNCS107887
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