Crescentic glomerulonephritis with dual positive anti-GBM and C-ANCA/PR3 antibodies

Antiglomerular basement membrane (anti-GBM) antibodies are more often accompanied by myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA) than by proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA). Both disease processes can affect the kidneys and/or the lungs. Patients with dual...

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Autores principales: Omotoso, Bolanle A., Cathro, Helen P., Balogun, Rasheed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438001/
https://www.ncbi.nlm.nih.gov/pubmed/29043135
http://dx.doi.org/10.5414/CNCS108666
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author Omotoso, Bolanle A.
Cathro, Helen P.
Balogun, Rasheed A.
author_facet Omotoso, Bolanle A.
Cathro, Helen P.
Balogun, Rasheed A.
author_sort Omotoso, Bolanle A.
collection PubMed
description Antiglomerular basement membrane (anti-GBM) antibodies are more often accompanied by myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA) than by proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA). Both disease processes can affect the kidneys and/or the lungs. Patients with dual positive disease may have an atypical presentation which may delay diagnosis and treatment. Here we report a case of crescentic glomerulonephritis associated with positive PR3-ANCA and anti-GBM antibodies who underwent both lung and kidney biopsies.
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spelling pubmed-54380012017-10-17 Crescentic glomerulonephritis with dual positive anti-GBM and C-ANCA/PR3 antibodies Omotoso, Bolanle A. Cathro, Helen P. Balogun, Rasheed A. Clin Nephrol Case Stud Case Report Antiglomerular basement membrane (anti-GBM) antibodies are more often accompanied by myeloperoxidase antineutrophil cytoplasmic antibody (MPO-ANCA) than by proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA). Both disease processes can affect the kidneys and/or the lungs. Patients with dual positive disease may have an atypical presentation which may delay diagnosis and treatment. Here we report a case of crescentic glomerulonephritis associated with positive PR3-ANCA and anti-GBM antibodies who underwent both lung and kidney biopsies. Dustri-Verlag Dr. Karl Feistle 2016-04-29 /pmc/articles/PMC5438001/ /pubmed/29043135 http://dx.doi.org/10.5414/CNCS108666 Text en © Dustri-Verlag Dr. K. Feistle http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Omotoso, Bolanle A.
Cathro, Helen P.
Balogun, Rasheed A.
Crescentic glomerulonephritis with dual positive anti-GBM and C-ANCA/PR3 antibodies
title Crescentic glomerulonephritis with dual positive anti-GBM and C-ANCA/PR3 antibodies
title_full Crescentic glomerulonephritis with dual positive anti-GBM and C-ANCA/PR3 antibodies
title_fullStr Crescentic glomerulonephritis with dual positive anti-GBM and C-ANCA/PR3 antibodies
title_full_unstemmed Crescentic glomerulonephritis with dual positive anti-GBM and C-ANCA/PR3 antibodies
title_short Crescentic glomerulonephritis with dual positive anti-GBM and C-ANCA/PR3 antibodies
title_sort crescentic glomerulonephritis with dual positive anti-gbm and c-anca/pr3 antibodies
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438001/
https://www.ncbi.nlm.nih.gov/pubmed/29043135
http://dx.doi.org/10.5414/CNCS108666
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