A Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro

Although human term placenta-derived primary cytotrophoblasts (pCTBs) represent a good human syncytiotrophoblast (STB) model, in vitro culture of pCTBs is not always easily accomplished. Y-27632, a specific inhibitor of Rho-associated coiled-coil containing kinases (ROCK), reportedly prevented apopt...

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Detalles Bibliográficos
Autores principales: Motomura, Kenichiro, Okada, Naoko, Morita, Hideaki, Hara, Mariko, Tamari, Masato, Orimo, Keisuke, Matsuda, Go, Imadome, Ken-Ichi, Matsuda, Akio, Nagamatsu, Takeshi, Fujieda, Mikiya, Sago, Haruhiko, Saito, Hirohisa, Matsumoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438149/
https://www.ncbi.nlm.nih.gov/pubmed/28542501
http://dx.doi.org/10.1371/journal.pone.0177994

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