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Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables
Cells’ biomechanical responses to external stimuli have been intensively studied but rarely implemented into devices that interact with the human body. We demonstrate that the hygroscopic and biofluorescent behaviors of living cells can be engineered to design biohybrid wearables, which give multifu...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438213/ https://www.ncbi.nlm.nih.gov/pubmed/28560325 http://dx.doi.org/10.1126/sciadv.1601984 |
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author | Wang, Wen Yao, Lining Cheng, Chin-Yi Zhang, Teng Atsumi, Hiroshi Wang, Luda Wang, Guanyun Anilionyte, Oksana Steiner, Helene Ou, Jifei Zhou, Kang Wawrousek, Chris Petrecca, Katherine Belcher, Angela M. Karnik, Rohit Zhao, Xuanhe Wang, Daniel I. C. Ishii, Hiroshi |
author_facet | Wang, Wen Yao, Lining Cheng, Chin-Yi Zhang, Teng Atsumi, Hiroshi Wang, Luda Wang, Guanyun Anilionyte, Oksana Steiner, Helene Ou, Jifei Zhou, Kang Wawrousek, Chris Petrecca, Katherine Belcher, Angela M. Karnik, Rohit Zhao, Xuanhe Wang, Daniel I. C. Ishii, Hiroshi |
author_sort | Wang, Wen |
collection | PubMed |
description | Cells’ biomechanical responses to external stimuli have been intensively studied but rarely implemented into devices that interact with the human body. We demonstrate that the hygroscopic and biofluorescent behaviors of living cells can be engineered to design biohybrid wearables, which give multifunctional responsiveness to human sweat. By depositing genetically tractable microbes on a humidity-inert material to form a heterogeneous multilayered structure, we obtained biohybrid films that can reversibly change shape and biofluorescence intensity within a few seconds in response to environmental humidity gradients. Experimental characterization and mechanical modeling of the film were performed to guide the design of a wearable running suit and a fluorescent shoe prototype with bio-flaps that dynamically modulates ventilation in synergy with the body’s need for cooling. |
format | Online Article Text |
id | pubmed-5438213 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-54382132017-05-30 Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables Wang, Wen Yao, Lining Cheng, Chin-Yi Zhang, Teng Atsumi, Hiroshi Wang, Luda Wang, Guanyun Anilionyte, Oksana Steiner, Helene Ou, Jifei Zhou, Kang Wawrousek, Chris Petrecca, Katherine Belcher, Angela M. Karnik, Rohit Zhao, Xuanhe Wang, Daniel I. C. Ishii, Hiroshi Sci Adv Research Articles Cells’ biomechanical responses to external stimuli have been intensively studied but rarely implemented into devices that interact with the human body. We demonstrate that the hygroscopic and biofluorescent behaviors of living cells can be engineered to design biohybrid wearables, which give multifunctional responsiveness to human sweat. By depositing genetically tractable microbes on a humidity-inert material to form a heterogeneous multilayered structure, we obtained biohybrid films that can reversibly change shape and biofluorescence intensity within a few seconds in response to environmental humidity gradients. Experimental characterization and mechanical modeling of the film were performed to guide the design of a wearable running suit and a fluorescent shoe prototype with bio-flaps that dynamically modulates ventilation in synergy with the body’s need for cooling. American Association for the Advancement of Science 2017-05-19 /pmc/articles/PMC5438213/ /pubmed/28560325 http://dx.doi.org/10.1126/sciadv.1601984 Text en Copyright © 2017, The Authors http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited. |
spellingShingle | Research Articles Wang, Wen Yao, Lining Cheng, Chin-Yi Zhang, Teng Atsumi, Hiroshi Wang, Luda Wang, Guanyun Anilionyte, Oksana Steiner, Helene Ou, Jifei Zhou, Kang Wawrousek, Chris Petrecca, Katherine Belcher, Angela M. Karnik, Rohit Zhao, Xuanhe Wang, Daniel I. C. Ishii, Hiroshi Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables |
title | Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables |
title_full | Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables |
title_fullStr | Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables |
title_full_unstemmed | Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables |
title_short | Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables |
title_sort | harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438213/ https://www.ncbi.nlm.nih.gov/pubmed/28560325 http://dx.doi.org/10.1126/sciadv.1601984 |
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