USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin

Synapse formation and growth are tightly controlled processes. How synaptic growth is terminated after reaching proper size remains unclear. Here, we show that Leon, the Drosophila USP5 deubiquitinase, controls postsynaptic growth. In leon mutants, postsynaptic specializations of neuromuscular junct...

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Detalles Bibliográficos
Autores principales: Wang, Chien-Hsiang, Huang, Yi-Chun, Chen, Pei-Yi, Cheng, Ying-Ju, Kao, Hsiu-Hua, Pi, Haiwei, Chien, Cheng-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438252/
https://www.ncbi.nlm.nih.gov/pubmed/28489002
http://dx.doi.org/10.7554/eLife.26886

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