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Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity

Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins constitute a microbial, adaptive immune system countering invading nucleic acids. Cas2 is a universal Cas protein found in all types of CRISPR-Cas systems, and its role is implicated in new space...

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Detalles Bibliográficos
Autores principales:	Ka, Donghyun, Hong, Suji, Jeong, Ugeene, Jeong, Migyeong, Suh, Nayoung, Suh, Jeong-Yong, Bae, Euiyoung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Crystallographic Association 2017
Materias:	ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438308/ https://www.ncbi.nlm.nih.gov/pubmed/28612041 http://dx.doi.org/10.1063/1.4984052

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