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Synthesis, docking study and biological evaluation of some new thiourea derivatives bearing benzenesulfonamide moiety
BACKGROUND: A series of novel N-(2, 6-dimethoxypyrimidin-4-yl)-4-(3-(aryl)thioureido) benzenesulfonamides 3a–t was synthesized by the addition of N-(2,6-dimethoxypyrimidin-4-yl)-4-isothiocyanatobenzenesulfonamide 2 to the appropriate aromatic amine. The structures of the synthesized compounds were i...
Autores principales: | Ghorab, Mostafa M., El-Gaby, Mohamed S. A., Soliman, Aiten M., Alsaid, Mansour S., Abdel-Aziz, Marwa M., Elaasser, Mahmoud M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438335/ https://www.ncbi.nlm.nih.gov/pubmed/29086825 http://dx.doi.org/10.1186/s13065-017-0271-7 |
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