Chitosan-Dextran sulfate coated doxorubicin loaded PLGA-PVA-nanoparticles caused apoptosis in doxorubicin resistance breast cancer cells through induction of DNA damage

To overcome the toxicity, pharmacokinetics and drug resistance associated with doxorubicin (DOX), a strategy was developed by encapsulating DOX- loaded-PLGA-PVA- nanoparticles within chitosan-dextran sulfate nanoparticles (CS-DS) [CS-DS-coated-DOX-loaded -PLGA-PVA-NP] and study the sensitivity again...

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Detalles Bibliográficos
Autores principales: Siddharth, Sumit, Nayak, Anmada, Nayak, Deepika, Bindhani, Birendra Kumar, Kundu, Chanakya Nath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438340/
https://www.ncbi.nlm.nih.gov/pubmed/28526868
http://dx.doi.org/10.1038/s41598-017-02134-z

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