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Combined use of metformin and atorvastatin attenuates atherosclerosis in rabbits fed a high-cholesterol diet

Statins are widely used to reduce cardiovascular risk. Unfortunately, some patients still experience cardiovascular events though prescribed with high-intensity statins. Metformin, an anti-diabetic drug, was reported to possess anti-atherosclerotic effects. Therefore, the experiments were designed t...

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Detalles Bibliográficos
Autores principales: Luo, Fei, Guo, Yuan, Ruan, Gui-yun, Long, Jun-ke, Zheng, Xi-long, Xia, Qin, Zhao, Shui-ping, Peng, Dao-quan, Fang, Zhen-fei, Li, Xiang-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438352/
https://www.ncbi.nlm.nih.gov/pubmed/28526884
http://dx.doi.org/10.1038/s41598-017-02080-w