Cargando…

EndophilinAs regulate endosomal sorting of BDNF-TrkB to mediate survival signaling in hippocampal neurons

The sorting of activated receptors into distinct endosomal compartments is essential to activate specific signaling cascades and cellular events including growth and survival. However, the proteins involved in this sorting are not well understood. We discovered a novel role of EndophilinAs in sortin...

Descripción completa

Detalles Bibliográficos
Autores principales: Burk, Katja, Murdoch, John D., Freytag, Siona, Koenig, Melanie, Bharat, Vinita, Markworth, Ronja, Burkhardt, Susanne, Fischer, Andre, Dean, Camin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438371/
https://www.ncbi.nlm.nih.gov/pubmed/28526875
http://dx.doi.org/10.1038/s41598-017-02202-4