Delineation of B-cell Epitopes of Salmonella enterica serovar Typhi Hemolysin E: Potential antibody therapeutic target

Hemolysin E (HlyE) is an immunogenic novel pore-forming toxin involved in the pathogenesis of typhoid fever. Thus, mapping of B-cell epitopes of Salmonella enterica serovar Typhi (S. Typhi) is critical to identify key immunogenic regions of HlyE. A random 20-mer peptide library was used for biopanni...

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Detalles Bibliográficos
Autores principales: Chin, Chai Fung, Lai, Jing Yi, Choong, Yee Siew, Anthony, Amy Amilda, Ismail, Asma, Lim, Theam Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438399/
https://www.ncbi.nlm.nih.gov/pubmed/28526816
http://dx.doi.org/10.1038/s41598-017-01987-8

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