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Sodium channel biophysics, late sodium current and genetic arrhythmic syndromes

Arrhythmias arise from breakdown of orderly action potential (AP) activation, propagation and recovery driven by interactive opening and closing of successive voltage-gated ion channels, in which one or more Na(+) current components play critical parts. Early peak, Na(+) currents (I (Na)) reflecting...

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Detalles Bibliográficos
Autores principales:	Chadda, Karan R., Jeevaratnam, Kamalan, Lei, Ming, Huang, Christopher L.-H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2017
Materias:	Invited Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438422/ https://www.ncbi.nlm.nih.gov/pubmed/28265756 http://dx.doi.org/10.1007/s00424-017-1959-1

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