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Levodopa-Carbidopa Intestinal Gel Pharmacokinetics: Lower Variability than Oral Levodopa-Carbidopa

In a double-blind, double-dummy, double-titration Phase 3 trial in advanced Parkinson’s disease (PD) patients, the efficacy and safety of Levodopa-carbidopa intestinal gel (LCIG) infusion were characterized relative to immediate-release oral levodopa-carbidopa (LC-oral) treatment. We present in this...

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Detalles Bibliográficos
Autores principales: Othman, Ahmed A., Rosebraugh, Matthew, Chatamra, Krai, Locke, Charles, Dutta, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438475/
https://www.ncbi.nlm.nih.gov/pubmed/28211816
http://dx.doi.org/10.3233/JPD-161042