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The Anti-Amyloid-β and Neuroprotective Properties of a Novel Tricyclic Pyrone Molecule
There is an urgent unmet need for new therapeutics for Alzheimer’s disease (AD), the most common cause of dementia in the elderly. Therapeutic approaches targeting amyloid-β (Aβ) and its downstream toxicities have become major strategies in AD drug development. We have taken a rational design approa...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
IOS Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438482/ https://www.ncbi.nlm.nih.gov/pubmed/28482635 http://dx.doi.org/10.3233/JAD-161175 |