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Transversions have larger regulatory effects than transitions
BACKGROUND: Transversions (Tv’s) are more likely to alter the amino acid sequence of proteins than transitions (Ts’s), and local deviations in the Ts:Tv ratio are indicative of evolutionary selection on genes. Whether the two different types of mutations have different effects in non-protein-coding...
Autores principales: | Guo, Cong, McDowell, Ian C., Nodzenski, Michael, Scholtens, Denise M., Allen, Andrew S., Lowe, William L., Reddy, Timothy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438547/ https://www.ncbi.nlm.nih.gov/pubmed/28525990 http://dx.doi.org/10.1186/s12864-017-3785-4 |
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