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MeDIP-seq and nCpG analyses illuminate sexually dimorphic methylation of gonadal development genes with high historic methylation in turtle hatchlings with temperature-dependent sex determination
BACKGROUND: DNA methylation alters gene expression but not DNA sequence and mediates some cases of phenotypic plasticity. Temperature-dependent sex determination (TSD) epitomizes phenotypic plasticity where environmental temperature drives embryonic sexual fate, as occurs commonly in turtles. Import...
Autores principales: | Radhakrishnan, Srihari, Literman, Robert, Mizoguchi, Beatriz, Valenzuela, Nicole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438563/ https://www.ncbi.nlm.nih.gov/pubmed/28533820 http://dx.doi.org/10.1186/s13072-017-0136-2 |
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