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Differential expression of VEGFR2 protein in HER2 positive primary human breast cancer: potential relevance to anti-angiogenic therapies

BACKGROUND: Clinically relevant predictive biomarkers to tailor anti-angiogenic therapies to breast cancer (BRC) patient subpopulations are an unmet need. METHODS: We analyzed tumor vascular density and VEGFR2 protein expression in various subsets of primary human BRCs (186 females; Mean age: 59 yea...

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Detalles Bibliográficos
Autores principales: Nasir, Aejaz, Holzer, Timothy R., Chen, Mia, Man, Michael Z., Schade, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438568/
https://www.ncbi.nlm.nih.gov/pubmed/28533703
http://dx.doi.org/10.1186/s12935-017-0427-5