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The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myeloma

We examined a set of 805 cases that underwent DNA sequencing using the FoundationOne Heme (F1H) targeted sequencing panel and gene expression profiling. Known and likely variant calls from the mutational data were analyzed for significant associations with gene expression defined translocation cycli...

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Detalles Bibliográficos
Autores principales: Stein, Caleb K., Pawlyn, Charlotte, Chavan, Shweta, Rasche, Leo, Weinhold, Niels, Corken, Adam, Buros, Amy, Sonneveld, Pieter, Jackson, Graham H., Landgren, Ola, Mughal, Tariq, He, Jie, Barlogie, Bart, Bergsagel, P. Leif, Davies, Faith E., Walker, Brian A., Morgan, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438613/
https://www.ncbi.nlm.nih.gov/pubmed/28427158
http://dx.doi.org/10.18632/oncotarget.15718