MicroRNA-494 promotes apoptosis and extracellular matrix degradation in degenerative human nucleus pulposus cells

PURPOSE: This study investigated the expression and function of the microRNA-494 in intervertebral disc degeneration (IDD). RESULTS: MicroRNA-494 expression was upregulated during IDD progression; its overexpression increased the expression of ECM catabolic factors such as matrix metalloproteinase a...

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Detalles Bibliográficos
Autores principales: Kang, Liang, Yang, Cao, Song, Yu, Zhao, Kangcheng, Liu, Wei, Hua, Wenbin, Wang, Kun, Tu, Ji, Li, Shuai, Yin, Huipeng, Zhang, Yukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438614/
https://www.ncbi.nlm.nih.gov/pubmed/28427186
http://dx.doi.org/10.18632/oncotarget.15838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438614/
https://www.ncbi.nlm.nih.gov/pubmed/28427186
http://dx.doi.org/10.18632/oncotarget.15838

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