HIF1α regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia

The standard treatment for Glioblastoma multiforme (GBM) is surgical resection and subsequent radiotherapy and chemotherapy. Surgical resection of GBM is typically restricted because of its invasive growth, which results in residual tumor cells including glioma stem cells (GSCs) and differentiated c...

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Detalles Bibliográficos
Autores principales: Wang, Pan, Lan, Chuan, Xiong, Shuanglong, Zhao, Xiuwen, Shan, You’an, Hu, Rong, Wan, Wenwu, Yu, Shuangjiang, Liao, Bin, Li, Guangzhi, Wang, Junwei, Zou, Dewei, Chen, Bing, Feng, Hua, Wu, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438632/
https://www.ncbi.nlm.nih.gov/pubmed/28427209
http://dx.doi.org/10.18632/oncotarget.15888

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