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miR-219-5p targets CaMKIIγ to attenuate morphine tolerance in rats

Morphine tolerance is a clinical challenge in pain management. Emerging evidence suggests that microRNA (miRNA) plays a regulatory role in the development of morphine tolerance. miR-219-5p (miR-219) targets calmodulin-dependent protein kinase II γ (CaMKIIγ) to activate central pain sensitization via...

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Detalles Bibliográficos
Autores principales:	Wang, Jian, Xu, Wei, Shao, Jiali, He, Zhenghua, Ding, Zhuofeng, Huang, Jiangju, Guo, Qulian, Zou, Wangyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438643/ https://www.ncbi.nlm.nih.gov/pubmed/28423675 http://dx.doi.org/10.18632/oncotarget.15997

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