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Aurora kinase A interacts with H-Ras and potentiates Ras-MAPK signaling

In cancer, upregulated Ras promotes cellular transformation and proliferation in part through activation of oncogenic Ras-MAPK signaling. While directly inhibiting Ras has proven challenging, new insights into Ras regulation through protein-protein interactions may offer unique opportunities for the...

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Detalles Bibliográficos
Autores principales:	Umstead, MaKendra, Xiong, Jinglin, Qi, Qi, Du, Yuhong, Fu, Haian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438655/ https://www.ncbi.nlm.nih.gov/pubmed/28177880 http://dx.doi.org/10.18632/oncotarget.15049

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